SUGGESTED READING- FROM AMERICAN PAIN SOCIETY VIA NEWSWISE

Antibiotics that can prevent infection and reduce postoperative pain...


Antibiotic Shows Analgesic Action Following Surgery

SUGGESTED READING- Aspirin May Fight Cancer by Slowing DNA Damage | ucsf.edu

The role of inflammation in cancer development has been receiving renewed attention. In this study the researchers found that aspirin could reduce cumulative  DNA damage  and reduce mitosis rate. The authors examine the hypothesis that aspirin's anti-inflammatory action  may be responsible for the anticancer effect.

Aspirin May Fight Cancer by Slowing DNA Damage | ucsf.edu

Looking forward to two days of intellectual stimulation, interesting discussion and riveting lectures with an exceptional set of guest speakers, panelists and participants on Evidence Based Oral & Maxillofacial Pathology 
The Living Legend Oration by Dr S.E Shroff
Guest lectures- by Dr. Anita Borges, Dr. Anil D'cruz, Dr. T. Chandrasekar, Dr R.V.  Subramanyam, Dr.T.V.Narayan, Dr. A.Mujib,
Dr. Ravi Prakash, Dr. Madhushankari S, Dr. Nandini  D.D.B.,
Panel Discussion: Dr. Anita Borges, Dr. Anil D'cruz, Dr. R.V. Subramanyam, Dr.T.V.Narayan Moderated by Dr. Mandana Donoghue

Block your calendar...
Be in Davangere on the 13th & 14th of September 2013

HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA- MEDSCAPE

A recent review by authors Marcus Monroe, MD; Chief Editor: Arlen D Meyers, MD, MBA on the Head & Neck cutaneous squamous cell carcinomas is a very interesting presentation of the topic that is detailed and up-to-date.
The article includes:

• Mucosal carcinomas
• History  of the carcinomas with the oldest case recorded
• Recent modification of TNM which takes into account high risk features and diameter of the lesion
• Pathogenesis ( which sadly has not focused much on the intraoral carcinomas)
• Details of diagnosis work up ( laboratory and imaging)
• Histopathology of variants
• Treatment considerations

This is an all in all great reading for those interested in Squamous cell carcinomas of Head & Neck.

To read the article go to:
http://emedicine.medscape.com/article/1965430-overview

LIVING MEDICAL E TEXT BOOK ON DERMATOLOGY

An interesting e-book from projects in knowledge..



http://lmt.projectsinknowledge.com/2132/

THE NUREMBERG CODE

 Another academic year and the inevitable haste to identify new dissertation topics are here. This seems like a good time to take a minute to recall the lessons learnt from the mistakes of the past.... Nothing that we do today should ever fail humanity and the medical profession to the extent of the experiments that caused the formation of  this code ... however there is a lesson that we can not afford to forget...

The Nuremberg Code

1. The voluntary consent of the human subject is absolutely essential. This means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, deceit, duress, over-reaching, or other ulterior form of constraint or coercion; and should have sufficient knowledge and comprehension of the elements of the subject matter involved, as to enable him to make an understanding and enlightened decision. This latter element requires that, before the acceptance of an affirmative decision by the experimental subject, there should be made known to him the nature, duration, and purpose of the experiment; the method and means by which it is to be conducted; all inconveniences and hazards reasonably to be expected; and the effects upon his health or person, which may possibly come from his participation in the experiment.
   The duty and responsibility for ascertaining the quality of the consent rests upon each individual who initiates, directs or engages in the experiment. It is a personal duty and responsibility which may not be delegated to another with impunity.
    
2. The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature.  
3. The experiment should be so designed and based on the results of animal experimentation and a knowledge of the natural history of the disease or other problem under study, that the anticipated results will justify the performance of the experiment.  
4. The experiment should be so conducted as to avoid all unnecessary physical and mental suffering and injury.  
5. No experiment should be conducted, where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects.  
6. The degree of risk to be taken should never exceed that determined by the humanitarian importance of the problem to be solved by the experiment.  
7. Proper preparations should be made and adequate facilities provided to protect the experimental subject against even remote possibilities of injury, disability, or death.  
8. The experiment should be conducted only by scientifically qualified persons. The highest degree of skill and care should be required through all stages of the experiment of those who conduct or engage in the experiment.  
9. During the course of the experiment, the human subject should be at liberty to bring the experiment to an end, if he has reached the physical or mental state, where continuation of the experiment seemed to him to be impossible.  
10. During the course of the experiment, the scientist in charge must be prepared to terminate the experiment at any stage, if he has probable cause to believe, in the exercise of the good faith, superior skill and careful judgement required of him, that a continuation of the experiment is likely to result in injury, disability, or death to the experimental subject.  

 "Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10", Vol. 2, pp. 181-182. Washington, D.C.: U.S. Government Printing Office, 1949.]

 http://www.hhs.gov/ohrp/archive/nurcode.html

MANDANA'S SUGGESTED READING FROM SCIENCE NEWS

In a recent study researchers from the University of California have found HSV-1 virus uses a component of the immune system to gain entry into cells...

Herpes virus exploits immune response to bolster infection
 

SUGGESTED READING: FROM ITHENITICATE PLAGIARISM PREVENTION BLOG by J. Bailey

The Challenge of Repeating Methods While Avoiding Plagiarism

Good guide lines on managing the methodology section of publications...

http://www.ithenticate.com/plagiarism-detection-blog/bid/94140e /The-Challenge-of-Repeating-Methods-While-Avoiding-Plagiarism

MANDANA'S SUGGESTED READING- BIOCOMPARE ARTICLE

Many Solid Tumors Carry Genetic Changes Targeted By Existing Compounds
According to the authors at least 2/3rd of all solid tumors carry at least one detectable mutation. Although the role played by these single gene mutations in the pathogensis and progression of the tumors is so far not clear. This is certainly an important finding... 

http://www.biocompare.com/Life-Science-News/138256-Many-Solid-Tumors-Carry-Genetic-Changes-Targeted-By-Existing-Compounds/

IMAGES FROM THE WEB - NEJM

Really interesting and rare..

NEJM - Image Challenge

MANDANA'S SUGGESTED READING - Cochrane overview of reviews

Medicines help smokers quit long term

Today most smokers are aware of the ill effects of their habit and many would genuinely like to give up.. doing so is however not easy . Here is a review of some pharmaceuticals that can help in giving up the habit..

http://evidentlycochrane.wordpress.com/2013/05/31/medicines-help-smokers-quit-long-term-finds-cochrane-overview-of-reviews/#more-456