HIV SCIENCE 2014 : International Science Symposium on HIV and Infectious Diseases : Home

HIV SCIENCE 2014 : International Science Symposium on HIV and Infectious Diseases : Home
30th January - 1st February 2014 ,Chennai , India
Early bird registration till 15th November 2013

The Status of Cancer 2013 - Cancer Progress Report

The Status of Cancer 2013 - Cancer Progress Report
Read about the burden of cancer and latest statistics in America with a mention of relevant numbers from the world.

Lifestyle Changes May Lengthen Telomeres, A Measure of Cell Aging | ucsf.edu

Lifestyle Changes May Lengthen Telomeres, A Measure of Cell Aging | ucsf.edu

JFK'S ADDRESS TO THE NATIONAL ACADEMY OF SCIENCES (OCTOBER 22, 1963)

It is amazing how relevant this speech is even after 50 years. Definitely worth hearing........

MELANOMA COLLECTION FROM EJC

The European Journal of cancer has made their collection of  research articles, reviews and clinical trials reports on Melanoma available at :
http://ejcancer-melanoma.com/content/melanoma-articles#!/?q=sss/5780/5781

DR. J.E.BOUQUOT'S POWERPOINT FILES AND OVER 3000 COPYRIGHT FREE PHOTOS

 Dr. J.E. Bouquot a very senior colleague from the United States has very generously shared a considerable number of his educational files in oral pathology on drop box the link for accessing the same is https://www.dropbox.com/sh/svnmqpjsx4r6owf/5_XkAMVwWC
You can freely access and share them

Dr. J. E. Bouquot
Adjunct Professor & Past Chair (Retired), Department of Diagnostic & Biomedical Sciences, University of Texas School of Dentistry at Houston, Houston, Texas 77054
Adjunct Professor, Department of Rural Health & Community Dentistry
Past Chair of the Department of Oral & Maxillofacial Pathology
West Virginia University School of Dentistry, Morgantown, WV 26506
Director of Research, The Maxillofacial Center for Education & Research, 212 Tibbs Road, Morgantown, WV 26508
Email: email: Jerry.Bouquot@uth.tmc.edu;
Websites: oralpath.com; maxillofacialcenter.com

GUEST SPEAKERS - Dr. Sarosh E Shroff Symposium

Dr. Anita Borges

To see more pictures of the event ... visit the living legends page https://www.facebook.com/pages/Living-Legends-Of-Oral-Maxillofacial-Pathology/228708777168308

POSTER PRESENTATION PRIZE WINNERS - THE LIVING LEGENDS OF ORAL & MAXILLOFACIAL PATHOLOGY SYMPOSIUM

DR SAROSH E SHROFF SYMPOSIUM ON EVIDENCED BASED ORAL & MAXILLOFACIAL PATHOLOGY

GROUP I

Dr. RANJINI M.R (POSTGRADUATE STUDENT)

COLLEGE: VYDEHI INSTITUTE OF DENTAL SCIENCES, BANGALORE

POSTER TITLE: EVALUATION OF EFFICACY OF DECALCIFYING AGENTS WITH ACCELERATORS ON TOOTH HISTOLOGY: A COMPARATIVE STUDY

GROUP II

Dr.Himanshi Chawla (POSTGRADUATE STUDENT)

COLLEGE: MAULANA AZAD INSTITUTE OF DENTAL SCIENCES, DELHI

POSTER TITLE: ANALYSIS OF DISTANCE BETWEEN EPITHELIUM AND MUSCLE IN ORAL SUBMUCOUS FIBROSIS - SEEKING NEW EVIDENCE 

MANDANA'S SUGGESTED READING ; "Medical Journals- a colossal problem of quality" by Richard Smith

A very interesting blog from the BMJ Group Blogs, that highlights the shortcomings of the current editorial systems of the medical journals and therefore the quality of data in them..
http://blogs.bmj.com/bmj/2013/09/24/richard-smith-medical-journals-a-colossal-problem-of-quality/

A comparative study of various decalcification techniques Prasad P, Donoghue M - Indian J Dent Res

A comparative study of various decalcification techniques Prasad P, Donoghue M - Indian J Dent Res

Latest publication of work done in Dept. of Oral & Maxillofacial Pathology CODS-Davangere.
Background : Study of fibrilar, cellular and sub cellular structures of mineralized tissues is only possible after the removal of the calcium apatite of these tissues by the process of demineralization.
Aims: The present study aims to evaluate six commonly used demineralizing agents to identify the best decalcifying agent.
Materials and Methods: The present study included six different decalcifying solutions: 10% formal nitric acid, 8% formal nitric acid, 10% formic acid, 8% formic acid, Perenyi's fluid and Ethylene Di-Amine Tetra Acetic Acid. eight samples of posterior mandible of rat were decalcified in each of the decalcifying solutions and subjected to chemical end-point test. Ehrlich's Hematoxylin stain was used.
Statistical Analysis Used: One way ANOVA was used for multiple group comparisons and Chi-square test was used for analyzing categorical data. P value of 0.05/less was set for statistical significance.
Results: Samples treated with EDTA showed the best overall histological impression and the tissue integrity were well preserved. Formal nitric of both the percentages 10 and 8% gave fairly good cellular detail and were rapid in their action.
Conclusion: The final impression led to the proposition that EDTA was indeed the best decalcifying agent available. However, with time constraint, the use of formal nitric acid is advocated.
Read the full article at the journal web site...

POSTERS LIST FOR THE SECOND LIVING LEGENDS OF ORAL & MAXILLOFACIAL PATHOLOGY SYMPOSIUM

1) V.N.Ratnakumari.T, A. NeethuTelagi,Ahmed Mujib B.R. Ameloblastomatous Gorlin's Cyst-A Rare Case Report. Bapuji Dental College and Hospital, Davangere

2) Kalpana Nuina, Aadithya B Urs, Shelly Arora. Massive Expansile Lesion in Pediatric Patient -A Diagnostic Challenge. Maulana Azad Institute of Dental Sciences, Delhi

3) Ranjini.M.R, K.Karpagaselvi, Jayalakshmi.K. Evaluation of Efficacy of Decalcifying agents with Acceletors On tooth Histology-A comparative Study. Vydehi Institute of Dental Sciences, Bangalore

4) Karthik Kona,,Ashwini Ramakrishna,,Madhushankari G.S.A Rare Entity Of Verruciform Xanthoma Coexisting With Oral Submucous Fibrosis-A Case Report. College of Dental Sciences, Davangere

5)  Himanshi Chawla, Aadithya B U, J Augustine.  Analysis Of Distance Between Epithelial and Muscle In Oral Submucous Fibrosis-Seeking New Evidence, Maulana Azad Institute of Dental Sciences, Delhi.

6) Sindhu Mati, K.Karpagaselvi, Jayalakshmi.K. Neurofibroma, Schwannoma and Fibroma-A Comparative Study. Vydehi Institute Of Dental Sciences, Bangalore.

7) Meghala Priya, Nandini D B, Mohan Kumar K P. Fibrous dysplasia - A Case report. College Of Dental Sciences, Davangere.

8) Sana Pathan, Shruthi K Patil. Evidence Based Approach to Clinical Problem. Bapuji Dental College and Hospital, Davangere

9) Babitha G.A. Desquamative gingivitis in Mucous Membrane Pemphigoid-A Case Report. College of Dental Sciences, Davangere.

10) Vikram Y, S SHiremath, K R Chatura, S B Patil. A case report of recurrent adenoid cystic carcinoma with cytohisto correlation. J.J.M. Medical College, Davangere.

11) Amrutha N, Anveeta Agarwal, Sanketh DS . Analysis of Human Papilloma Virus in Oral Squamous Cell Carcinoma Using P16 - An Immunohistochemical Study. M S Ramaiah Dental College, Bangalore.

12) A.Saileela, Vidya G S, Spoorthi B R. Flipside of Adhesives And Its Compatibility In The Laboratory-A Comparative Study. M S Ramaiah Dental College, Bangalore.

13) Vidya.G.S, A Saileeela,Spoorthi B R. Dandy Fever-Scope Of Dribble In Its Invesigation. M S Ramaiah Dental College,Bangalore.

14) A.Yamunadevi, Selvamani. M, Madhushankari G. S, Praveen S. Basandi. Keratinization in odontogenic cysts – From Toller to today – An Evidence Based Learning. Vivekanandha Dental College for Women, Namakkal (TN).

15) Anubhav Agarwal, KSN Siva Bharani, Rajay AD Kamath. Parathyroid Adenoma: A Rare Case with Mandibular Brown Tumor. College of Dental Sciences, Davangere.

16) Jomi. Porinchu, KSN Siva Bharani, Kiran H Y. Sialadenitis Secondary to Sialolithiasis of Left Submandibular Gland. College of Dental Sciences, Davangere.

17) Akshaya.S.Dutta, Shashidara.R. Neurovascular Hemartoma- a lesion searching for a name. Coorg Institute of  Dental Sciences,Virajpet.

18) Ketki Sali, Shashidara.R. Radicular cyst -A Rare Case Report. Coorg Institute of Dental Sciences, Virajpet.

19) Roshini V, Shashidara R. Medical management of Oral Lichen Planus: An evidence based study. Coorg Institute of Dental Sciences, Virajpet.

LIVING LEGENDS SYMPOSIUM UPDATE

The Dr. Sarosh E. Shroff Symposium on Evidence Based Oral & Maxillofacial Pathology:
13th & 14th September 2013
The symposium has received 12 CDE points from the Karnataka State Dental Council.
The last date for scientific abstract submission has been extended to 25th of August 2013..
For  more details visit:
https://www.facebook.com/pages/Living-Legends-Of-Oral-Maxillofacial-Pathology/228708777168308

For enquiries contact
Organizing Secretary                
Dr. Nandini D.B
nanni@rediff.com

A REPORT ON THE VISIT TO THE CENTRE FOR FORENSIC AND LEGAL MEDICINE, UNIVERSITY OF DUNDEE, DUNDEE (SCOTLAND), UK- By Dr Ashith Acharya

In  this detailed report by Dr Ashith read about, the DCI's views on master of forensic odontology, research collaboration, faculty placement and the Scottish Travel prize


Following the invitation from Professor Derrick J. Pounder, Director of the Centre for Forensic and Legal Medicine, University of Dundee, Scotland, UK to the President of the IAFO, Professor S. Balagopal, I was selected to represent the IAFO on a visit to the Centre in UK for wide-ranging discussions. Upon the suggestion of Professor Pounder, I visited them from 19–31 May 2013. During the two-week visit, the following issues were discussed:

The practice of forensic odontology in India (lectures and practical session on age estimation)

            I was scheduled to deliver two lectures—one on age estimation, giving some case examples and practical issues encountered in India, and another on the forensic odontology cases referred to my department in Dharwad. 

            Both lectures were organised in the Dental School of the university.  The lectures were followed by extensive question-answer sessions. While both presentations appeared to have been well-received, the age estimation lecture, in particular, seemed to have made greater impact.

            In addition, I conducted a two-hour practical session on radiographic age estimation for the students of the Master of Forensic Odontology (MFO) course (the forensic odontology postgraduate course offered at Dundee).

Centre for Forensic and Legal Medicine
at the University of Dundee, Scotland, UK

 Possible research collaborations between faculty at Dundee and IAFO members

            Areas of common interest in research were explored with Dr. Andrew Forgie Supervisor of the MFO course, as well as faculty at the Centre of Anatomy and Human Identification. 

In forensic odontology, comparative dental identification and bite mark analyses were two areas that were put forward by Dr. Forgie. One suggestion made was to obtain dental casts from faculty in India, which could be 3D-scanned in Dundee and the data shared in bite mark studies and other research collaborations.

            Discussion on research collaborations with faculty members of the Centre of Anatomy and Human Identification explored skeletal development, data of the face (e.g., facial soft tissue thickness) and skull (e.g., skull anatomic features). These data, too, could be shared with faculty members of that university and members of the IAFO in mutually beneficial research projects.

Professor Derrick J. Pounder

DCI approval of Master of Forensic Odontology course

            Professor Pounder was very keen to learn about the modality for Dental Council of India (DCI) recognition of the one-year MFO course. At the outset, I informed him that the DCI required the course to be at least two years of duration, which will allow it to be equated with a PG Diploma in the Indian context; a three-year course would allow it to become eligible for recognition as a degree equivalent to MDS in India. While there was some acknowledgement for the course to have an extension of one year to make it a two-year programme, Professor Pounder believed that, having a three-year course may be difficult to achieve since the depth of the subject may not necessitate such a long-drawn programme.

            Later, he also wondered whether the MFO course should seek any form of DCI recognition—he pointed out that, not having DCI approval may make it more difficult for students completing their MFO course from Dundee to be appointed as a faculty member in a dental college in India, but there is nothing that prevents one from practicing forensic odontology in India. He contended that technically, even without DCI recognition, one can practice the specialty of forensic odontology in India; also, colleges can appoint someone with such a qualification as their faculty and even promote them based on their requirements and performance of the faculty member. He acknowledged, however, that it may make it more difficult for colleges to appoint and promote someone without a DCI-recognised qualification since the college will not be able to show such faculty members as a DCI-recognised faculty during DCI inspections.

 

Meeting with the Master of Forensic Odontology course students to discuss their future plans and routes to work in India

Dental colleges may, today, be more receptive to employing qualified forensic odontologists, partly since it may serve as an added benefit in aspects of the college’s quality and in NAAC accreditation, which is mandated by the DCI; in addition, colleges may also have a genuine interest in being a forerunner in introducing new specialties. Furthermore, this may give such colleges a head-start in initiating MDS in forensic odontology in a few years time (MDS in forensic odontology was approved by the DCI in May 2012). 

     

The two students from India enrolld in the Master of Forensic Odontology course, Subrahmanyeswara (left) and Sudheer (right), along with Dr. Andrew Forgie (centre-right) and I.

 Faculty requirement for guiding the Master of Forensic Odontology course
Professor Pounder’s proposes to employ  a qualified forensic odontology faculty member, preferably from India, to undertake some of the guidance of students enrolled in the Master of Forensic Odontology course.  As an incentive, such faculty from India could also simultaneously undertake a Masters by Research. The faculty position will be advertised shortly.

Scottish Travel Prize

            Professor Pounder proposed a ‘Scottish Travel Prize’ for the best paper presentation at the upcoming 11^th IAFO conference in Vijayawada, Andhra Pradesh, on 21-22 September 2013. He suggested that the IAFO choose a panel of three members who in-turn would select a shortlist of the best oral presentations at the conference. The abstracts of these papers will be sent to Professor Pounder for a final decision on the ‘winner’. The winner of the prize will get the opportunity to travel to the University of Dundee for a period of two weeks (all expenses paid by the University) and the chance to interact with students and faculty there, as well as observe the practice of the specialty. The tentative dates for the visit are mid-May 2014.

Overall, the visit to the University of Dundee was quite satisfying—it put in perspective some of the differences in the approach to the practice of the specialty in India and the UK and the respective areas of professional interest; it has also opened the doors for future collaborations on a wide range of topics in forensic dentistry and anthropology, as well as possibly creating new avenues for faculty positions for qualified forensic dentists from India.

Dr. Ashith B. Acharya

Honorary Secretary, IAFO

&

Associate Professor and Head

Department of Forensic Odontology

SDM College of Dental Sciences & Hospital

Sattur, Dharwad – 580009

Karnataka

DR S E SHROFF LIVING LEGENDS SYMPOSIUM ON EVIDENCE BASED ORAL & MAXILLOFACIAL PATHOLOGY

Down load the detailed brochure at https://www.dropbox.com/s/y54ogbskia438rh/Dr.%20S.E%20.%20Shroff%20Living%20legends%20symposium.pdf

Registration form - https://www.dropbox.com/s/fdnjwmsbatfcinu/Living%20Legends%20Symposium%20Registration%20form.pdf

Scientific (poster) presentation form- https://www.dropbox.com/s/3v3vp8bvc7g3zgp/Living%20legends%20Symposium%20Poster%20abstract.pdf 

A model road map to the practice of forensic odontology. Donoghue M - J Forensic Dent Sci

Guest editorial......
Forensic odontology/dentistry-a relatively young branch in India-successfully crossed the first milestone in the life of a specialty, upon its inclusion in the Bachelor of Dental Surgery (BDS) curriculum in 2007 and recognition as a post graduate subject, in 2012. ^[1] The next milestone to cross is to achieve greater inclusion in the forensic team. To achieve this, greater numbers of forensic dentists need to move from theory to practice. Those who choose to go the distance will find the following model road map helpful:

Read the full article
A model road map to the practice of forensic odontology Donoghue M - J Forensic Dent Sci

REQUEST FOR ORAL SARCOIDOSIS PHOTOMICRROPGRAPH

Dear all, a colleague is requesting our help...
Dr Pavan Patil who  is an  Oral & Maxillofacial Surgeon  requires a photomicrograph of oral sarcoidosis for his review article on oral sarcoidosis for the oral health care provider. He assures me he will acknowledge the contribution in the article.
please let me know if you can help him by placing a comment on this post...
 

CONTRIBUTIONS FOR THE LIFE OF A LEGEND BOOKLET- ON THE PROFESSIONAL LIFE OF DR SAROSH E SHROFF

LIVING LEGENDS OF ORAL AND MAXILLOFACIAL PATHOLOGY AND MICROBIOLOGY:

In the year 2011 , we at the Department of Oral & Maxillofacial Pathology & Microbiology College of Dental Sciences(CODS) Davangere, had a vision to honor the contributions made by various doctors , teachers and colleagues to the establishment and development of our specialty in India. As we all know  it is not possible to appropriately acknowledge everyone’s contributions through  orations at the National Conference and The PG Convention. Considering this we felt that we could honor such Living Legends of Oral and Maxillofacial Pathology  in an event that would be dedicated to one legend each time.

We then went ahead with turning the vision into reality by conducting the  first National Level Living Legends Symposium by conducting the Dr. MV LELE Symposium On Oral & Maxillofacial Bone Pathology in September 2011, in association with Academy Of Continuing Education (ACE-CODS). The event which was attended by over 150 delegates from across the country was  highly successful both in terms of scientific deliberations and in familiarizing a number of young oral pathologists with Dr. MV Lele.

This year we hope to conduct another successful event with your support. This years Living Legend is Dr . Sarosh E. Shroff. During the event we hope to outline Sir’s contributions and professional journey. A booklet will also be prepared containing details of Sirs professional life, photos and messages of  students and colleagues.

The booklet of life of Living Legend Dr. MV Lele prepared during the last symposium is available at  https://www.dropbox.com/s/mu0hau9ag7ddxs1/Dr.%20M.V.%20Lele%20the%20living%20legend%202011.pdf. 

 Kindly upload your messages  and thoughts of Dr. Shroff and photos with him by visiting the FB page Living Legends Of Oral & Maxillofacial Pathology ,

While on the page  if you also hit the like button you will get regularly updated  information of the current and future events.

Looking forward to hearing from you and meeting you at the event 

On Behalf of The Department of Oral & Maxillofacial Pathology & Microbiology

College of Dental Sciences,

Davangere

SUGGESTED READING- FROM AMERICAN PAIN SOCIETY VIA NEWSWISE

Antibiotics that can prevent infection and reduce postoperative pain...


Antibiotic Shows Analgesic Action Following Surgery

SUGGESTED READING- Aspirin May Fight Cancer by Slowing DNA Damage | ucsf.edu

The role of inflammation in cancer development has been receiving renewed attention. In this study the researchers found that aspirin could reduce cumulative  DNA damage  and reduce mitosis rate. The authors examine the hypothesis that aspirin's anti-inflammatory action  may be responsible for the anticancer effect.

Aspirin May Fight Cancer by Slowing DNA Damage | ucsf.edu

Looking forward to two days of intellectual stimulation, interesting discussion and riveting lectures with an exceptional set of guest speakers, panelists and participants on Evidence Based Oral & Maxillofacial Pathology 
The Living Legend Oration by Dr S.E Shroff
Guest lectures- by Dr. Anita Borges, Dr. Anil D'cruz, Dr. T. Chandrasekar, Dr R.V.  Subramanyam, Dr.T.V.Narayan, Dr. A.Mujib,
Dr. Ravi Prakash, Dr. Madhushankari S, Dr. Nandini  D.D.B.,
Panel Discussion: Dr. Anita Borges, Dr. Anil D'cruz, Dr. R.V. Subramanyam, Dr.T.V.Narayan Moderated by Dr. Mandana Donoghue

Block your calendar...
Be in Davangere on the 13th & 14th of September 2013

HEAD AND NECK CUTANEOUS SQUAMOUS CELL CARCINOMA- MEDSCAPE

A recent review by authors Marcus Monroe, MD; Chief Editor: Arlen D Meyers, MD, MBA on the Head & Neck cutaneous squamous cell carcinomas is a very interesting presentation of the topic that is detailed and up-to-date.
The article includes:

• Mucosal carcinomas
• History  of the carcinomas with the oldest case recorded
• Recent modification of TNM which takes into account high risk features and diameter of the lesion
• Pathogenesis ( which sadly has not focused much on the intraoral carcinomas)
• Details of diagnosis work up ( laboratory and imaging)
• Histopathology of variants
• Treatment considerations

This is an all in all great reading for those interested in Squamous cell carcinomas of Head & Neck.

To read the article go to:
http://emedicine.medscape.com/article/1965430-overview

LIVING MEDICAL E TEXT BOOK ON DERMATOLOGY

An interesting e-book from projects in knowledge..



http://lmt.projectsinknowledge.com/2132/

THE NUREMBERG CODE

 Another academic year and the inevitable haste to identify new dissertation topics are here. This seems like a good time to take a minute to recall the lessons learnt from the mistakes of the past.... Nothing that we do today should ever fail humanity and the medical profession to the extent of the experiments that caused the formation of  this code ... however there is a lesson that we can not afford to forget...

The Nuremberg Code

1. The voluntary consent of the human subject is absolutely essential. This means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, deceit, duress, over-reaching, or other ulterior form of constraint or coercion; and should have sufficient knowledge and comprehension of the elements of the subject matter involved, as to enable him to make an understanding and enlightened decision. This latter element requires that, before the acceptance of an affirmative decision by the experimental subject, there should be made known to him the nature, duration, and purpose of the experiment; the method and means by which it is to be conducted; all inconveniences and hazards reasonably to be expected; and the effects upon his health or person, which may possibly come from his participation in the experiment.
   The duty and responsibility for ascertaining the quality of the consent rests upon each individual who initiates, directs or engages in the experiment. It is a personal duty and responsibility which may not be delegated to another with impunity.
    
2. The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature.  
3. The experiment should be so designed and based on the results of animal experimentation and a knowledge of the natural history of the disease or other problem under study, that the anticipated results will justify the performance of the experiment.  
4. The experiment should be so conducted as to avoid all unnecessary physical and mental suffering and injury.  
5. No experiment should be conducted, where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects.  
6. The degree of risk to be taken should never exceed that determined by the humanitarian importance of the problem to be solved by the experiment.  
7. Proper preparations should be made and adequate facilities provided to protect the experimental subject against even remote possibilities of injury, disability, or death.  
8. The experiment should be conducted only by scientifically qualified persons. The highest degree of skill and care should be required through all stages of the experiment of those who conduct or engage in the experiment.  
9. During the course of the experiment, the human subject should be at liberty to bring the experiment to an end, if he has reached the physical or mental state, where continuation of the experiment seemed to him to be impossible.  
10. During the course of the experiment, the scientist in charge must be prepared to terminate the experiment at any stage, if he has probable cause to believe, in the exercise of the good faith, superior skill and careful judgement required of him, that a continuation of the experiment is likely to result in injury, disability, or death to the experimental subject.  

 "Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10", Vol. 2, pp. 181-182. Washington, D.C.: U.S. Government Printing Office, 1949.]

 http://www.hhs.gov/ohrp/archive/nurcode.html

MANDANA'S SUGGESTED READING FROM SCIENCE NEWS

In a recent study researchers from the University of California have found HSV-1 virus uses a component of the immune system to gain entry into cells...

Herpes virus exploits immune response to bolster infection
 

SUGGESTED READING: FROM ITHENITICATE PLAGIARISM PREVENTION BLOG by J. Bailey

The Challenge of Repeating Methods While Avoiding Plagiarism

Good guide lines on managing the methodology section of publications...

http://www.ithenticate.com/plagiarism-detection-blog/bid/94140e /The-Challenge-of-Repeating-Methods-While-Avoiding-Plagiarism

MANDANA'S SUGGESTED READING- BIOCOMPARE ARTICLE

Many Solid Tumors Carry Genetic Changes Targeted By Existing Compounds
According to the authors at least 2/3rd of all solid tumors carry at least one detectable mutation. Although the role played by these single gene mutations in the pathogensis and progression of the tumors is so far not clear. This is certainly an important finding... 

http://www.biocompare.com/Life-Science-News/138256-Many-Solid-Tumors-Carry-Genetic-Changes-Targeted-By-Existing-Compounds/

IMAGES FROM THE WEB - NEJM

Really interesting and rare..

NEJM - Image Challenge

MANDANA'S SUGGESTED READING - Cochrane overview of reviews

Medicines help smokers quit long term

Today most smokers are aware of the ill effects of their habit and many would genuinely like to give up.. doing so is however not easy . Here is a review of some pharmaceuticals that can help in giving up the habit..

http://evidentlycochrane.wordpress.com/2013/05/31/medicines-help-smokers-quit-long-term-finds-cochrane-overview-of-reviews/#more-456

MANDANA'S SUGGESTED READING- Designing Tomorrow's Vaccines — NEJM

An intersting  review on vaccines from NEJM ( free -full text)
Designing Tomorrow's Vaccines — NEJM

IMAGES FROM THE WEB- Red Melanoma — NEJM

This is a particularly intersting presentation of Melanoma... well worth a look.
Red Melanoma — NEJM

MANDANA'S SUGGESTED READING- AN INTERSTEING PAPER FROM CANCER PREVENTION RESEARCH

An intersting article that reports a phase II trial of a serine protease inhibitor isolated from soybean.. "Bowman Birk inhibitor concentrate & oral  leukoplkia : A randomized phase II b trial" by W.B. Armstrong et al
Find the full text of the article at :

http://cancerpreventionresearch.aacrjournals.org/content/6/5/410.full

MANDANA'S SUGGESTED READING- FORENSIC MEDICINE RESOURCES

An interesting blog with a wide range of information on forensic medicine..

http://eforensicmed.blogspot.in/

2013 - ANNUAL MEETING OF THE AMERICAN ACADEMY OF ORAL & MAXILLOFACIAL PATHOLOGY

June 14th to June 19th 2013
Portland , Oregon
Venue: Hilton Portland & Executive Tower 
More details at :

http://www.aaomp.org/annual-meeting

PUBLICATIONS FROM THE DEPARTMENT- EFFECT OF VITALITY ON TRANSLUCENT DENTIN- A STUDY

Selvamani M, Madhushankari G S, Basandi P S, Donoghue M, Nayak V, Diwakar G. Effect of Vitality on Translucent Dentine – A Study. J Int Oral Health 2013; 5(2):1-7.


ABSTRACT
Background: Sclerosis of dentinal tubules may be a response to pathological or physiological insult in the crown & root. The mechanism by which apical translucency is produced is still uncertain. The increase in size of the apical zone of sclerotic dentin in human teeth has been used often in forensic science as a method of age estimation.
However, only few studies have been done to compare percentage of translucency between vital and non-vital teeth. Conflicting concepts exist regarding the amount of translucent dentin in the vital & non vital teeth and correlation of this variation with age of the subject.
Aims: To investigate the amount and distribution of apical translucent dentin in group-matched vital and non-vital teeth.
Materials and Methods: Study was conducted on 70 extracted teeth, which were subjected for vitality test before extraction, and divided into two groups (vital & non-vital teeth) with a minimum of 35 teeth in each group. Ground sections of 150µ thickness were observed under Stereomicroscope and photographed. The distribution of area and length was measured on the images captured, using PROPLUS IMAGE ANALYSIS SOFTWARE version 4.1.0.0 software.
Results and Conclusions: The present study revealed significant differences (p<0.05) in apical translucency of
dentin, when both vital and non-vital teeth types were compared. There was more apical translucency present in non-vital when compared with vital teeth at any given age.
Keywords: Apical translucency; vital teeth; non-vital teeth.
Read the article at ...........

http://www.jioh.in/eJournals/ShowText.aspx?ID=16&Type=FREE&TYP=TOP&IN=_eJournals/images/JPLOGO.gif&IID=2&Value=1&isPDF=YES

MANDANA'S SUGGESTED READING- EDITOR'S PICK FROM AMERICAN ASSOCIATION FOR CANCER RESEARCH

Monthly editor's pick from the AACR journals -- Find the recommended articles for March at

http://www.aacrjournals.org/site/SpecialPages/editors_picks.xhtml

2nd Living Legends Symposium of Oral & Maxillofacial Pathology

The second Living Legends Symposium has been scheduled for the 13th & 14th of September 2013.
Watch this space or visit the FB page http://www.facebook.com/pages/Living-Legends-Of-Oral-Maxillofacial-Pathology/228708777168308

Registration dates and details will be announced shortly

MANDANA'S SUGGESTED READING - COCHRANE REVIEW ON CUTANEOUS LEISHMANIASIS

Leishmaniasis is a parasitic vector dependent disease that manifests either as a visceral or cutaneous disease. The exposed parts of skin (like the neck and face) are often affected, making it necessary for oral pathologists and dentists to be familiar with the disease.
While endemic in parts of Rajasthan and Himachal Pradesh it can be seen in any part of the country....

Read the cochrane review at ...............
http://www.thecochranelibrary.com/details/editorial/4536171/Cochrane-Reviews-on-neglected-diseases-the-case-of-cutaneous-leishmaniasis.html

MANDANA'S SUGGESTED READING- SCIENCE DAILY

Estrogen plus progestin use linked with increased breast cancer incidence and mortality

A very relevant article to us considering the presence of estrogen receptors on some salivary gland neoplasms...

MANDANA'S SUGGESTED READING- SCIENCE NEWS

You don't 'own' your own genes: Researchers raise alarm about loss of individual 'genomic liberty' due to gene patents

This is something really interesting ...
As time passes we may know more and more about what affects our health and yet have less and less right to deal with it...

IMAGES FROM THE WEB - NEJM

NEJM - Image Challenge
Deep palatal ulcer and erosion of teeth...

MANDANA'S SUGGESTED READING- SCIENCE DAILY NEWS

Dwelling on stressful events can increase inflammation in the body, 

Many oral  mucosal conditions are believed to be stress related... one's thoughts can actually bring about an inflammatory response and logically some inflammatory changes.. here is some news on that.
The next time we are asking our patients if they are under any stress we will need to also ask if they were under stress previously and tend to brood on it....
Science news has given a very good overview of the topic .

CDE REPORT- “ORAL WHITE LESIONS/PRECURSOR LESIONS” DR. PETER REICHART

 In his presentation Professor Reichart highlighted:
·         The necessity of being aware of the entire range of white lesions that affect oral mucosa including some potentially malignant (PM) lesions  to avoid over treatment.
·         Lesions such as leukoedema, frictional keratosis, morsicatio,  smokers palate, chemical burns and white spongy nevus  need to be differentiated from leukoplakia, lichen planus, lichenoid lesions and oral sub mucous fibrosis.
·         Clinical differentiation of the lesions with and without out malignant potential require a biopsy. However knowledge of specific features can assist in identifying high risk white lesions and surface changes.
·         A lesion should be suspected  to be innocuous when  :

o   Appears in an unlikely site for  Squamous cell carcinoma( SCC)-  like surface of tongue, tip of tongue(plaque type Lichenplanus more common),  gingiva and palate

o   Occurs in Children or the very young.

o   Unlikely morphology- Triangular and bilateral (most likely – cheek biting), Bilateral Retroangular homogenous in heavy smokers,

o   White lesions that are scrapable, like Pseudomembranous candidiasis, which  is wipable/scrapable.

o   Lesions identifiable as other entities such as

§  Smoker’s palate or stomatitis nicotina palatini. (It is caused by heat rather than the nicotine and the site may be more resistant to malignant change due to heavy keratinization of the palate)

§  Smoker’s melanosis dark brownish black minute spots on mucosa first described by Swedish researcher Heldin.  Heavy smokers may show bilateral brownish tinge  of OMM that shows no malignant transformation

·         Optimal management –

·         Biopsy/s to rule out/identify/grade dysplastic change.

·         Early intervention… Best approach is removal  by CO2 laser.

·         No known treatment that can prevent malignant transformation  therefore, recall important

o   Homogenous leukoplakia – 3-6 months

o   Non homogenous leukoplakia – 6- 12 months

MANDANA'S SUGGESTED READING- 7 Plagiarism Myths Debunked - ITHENICATE

7 Plagiarism Myths Debunked
The author of this article which is also available as a web cast has made a laudable effort to bust seven common myths on plagiarism by tackling seven common myths:
" Plagiarism is not a rising problem"
" Plagiarism Is Mostly a Problem Among Students and Not Professionals"

"The Plagiarism Issue is Blown Out of Proportion" 

"Plagiarism is Harmless"

"Plagiarism is Primarily a Problem in Non-English Speaking Countries"

" Almost All Plagiarists Get Caught"

"There is Nothing Wrong with Self-Plagiarism"

 

Read the full article or watch the webcast:

http://www.ithenticate.com/7-plagiarism-myths-debunked/

 

CDE REPORT

UPDATE IN ORAL MEDICINE AND PATHOLOGY WITH ORAL IMAGING AND STRATEGIES FOR RESEARCH

 

A 2 day lecture series by Prof Peter A. Reichart& Dr Michael M. Bornstein was conducted by Department of Oral Medicine & Radiology K.L.E. Institute of Dental Science Bangalore & International Association of General Dentistry (IAGD) on 1st & 2ndof March 2013. The lectures were a scientific treat covering diverse areas of Oral Medicine & Pathology. The lectures included oral cancer & precancer, odontogenic cysts & tumors, mucosal lesions, 3 dimensional imaging in dental medicine and the need for research. The lectures were made particularly interesting by the speaker’s clinical experiences which they shared generously with the audience. Successfully, keeping everyone in the auditorium for two full days ...
 Lecture highlights in the next few days………..



Prof. Dr. Peter A. Reichart 
 

Dr. Michael M. Bornstein 



MANDANA'S SUGGESTED READING: http://www.theatlantic.com-the-benefits-of-optimism-are-real

Here is an intersting article on the benefits of Optimism. We are often faced with a depressing task of informing patients of life threatening diseases. when we feel there is no hope we do transfer the feeling to the patients and their family. This is an interesting article that can remind us to view things differently and not lose hope...

http://www.theatlantic.com/health/archive/2013/03/the-benefits-of-optimism-are-real/273306/

CONFERENCES 2013- 11th NATIONAL CONFERENCE OF IAFO

National Conference of Indian Association of Forensic Odontology
21st & 22nd September 2013,Vijayawada, Andhra Pradesh
Venue Hotel Gateway, Taj
Early Bird - till July 31st
Further details at
Conference secretariat: e-mail : 11forensic@gmail.com
 http://11iafo2013.com/ (under construction)
 

CONFERENCES 2013- XXII NATIONAL CONFERENCE OF THE IAOMP

8th to 10th November 2013, Mumbai
For information and registration visit the conference web site..
http://iaompmumbai2013.com/
 

CONFERENCES 2013- INTERNATIONAL CONGRESS OF I.O.F.O.S.

28th-30th August 2013, Florence, Italy
Early Bird Registration - 15th June 2013
http://congress.iofos.eu/

CONFERENCES 2013- FDI WORLD DENTAL CONGRESS

FDI 2013 Istanbul

28th-31st August 2013, Istanbul -Turkey

Early Bird Registration- 31st May 2013
http://www.fdi2013istanbul.org/INT/

IMAGES FROM THE WEB- NEJM

NEJM - Image Challenge
Bilatral multiple nodules.........

MANDANA'S SUGGESTED READING- ED'S NOTES ON PREVENTING "F" S

As teachers we are increasingly faced with falling grades, attendance and what we perceive to be a lack of interest on the student's part. Here is an insightful lecture from Dr Ed Friedlander that should help the entire class to not only avoid failure but also enhance over all learning...
To see the lecture notes visit :

http://www.pathguy.com/lectures/f-talk.htm
 

MANDANA'S SUGGESTED READING- ADVERSE EFFECTS OF HOMEAOPATHY

 

Homeopathy is the most popular form of alternative medicine. Most of us come across patients, family & friends who are staunch believers in its safety. Here is an article that does not in any way discredit Homeopathy but highlights its ability to be unsafe and cause adverse effects, specially if taken in place of essential allopathic remedy.

A Systematic Review of Published Case Reports and Case Series

P. Posadzki, A. Alotaibi, E. Ernst,

Int J Clin Pract. 2012;66(12):1178-1188

Full article is availabe at Medscape
http://www.medscape.com/viewarticle/777749

IMAGES FROM THE WEB- NEJM - IMAGE CHALLENGE

NEJM - Image Challenge

CONFERENCES 2013- XIII NATIONAL POSTGRADUATE CONVENTION IAOMP

The XIII National Post Graduate convention of the IAOMP at Thirupathi is scheduled for the 10th & 11th of July 2013.
Visit the convention web site for details & registration. (Early Bird Registration upto 28th Feb 2013)

http://www.opthirupati.com/

IMAGES FROM THE WEB - Papulonodular Syphilis — NEJM

Papulonodular Syphilis — NEJM

MANDANA'S SUGGESTED READING- HOW TO REVIEW AN ARTICLE

SPRINGER ACADEMY
Increasing number of publications and journals means almost all academicians will be called on review papers at some point of time. To avoid being baffled by the task at hand, visit and read the relevant content on the web site at the following URL.

http://www.springer.com/authors/journal+authors/peer-review-academy?SGWID=0-1741413-12-959504-0

CONFERENCES 2013- 26TH ANNUAL CONFERENCE ISDR

 26th Annual conference of the Indian Society of Dental Reserach
3rd-6th October, New Delhi
Registraions are open for national & international Participants.
For more details visit

http://isdr2013.com/

 

 

MANDANA'S SUGGESTED READING- HIV FACT SHEET 2012

Global HIV infections and death caused by HIV have reduced considerably, however, the battle is no where near over as this latest fact sheet shows...

Read the details by downloading the latest global HIV/AIDS epidemic fact sheet

http://www.kff.org/hivaids/upload/3030-17.pdf

MANDANA'S- SUGGESTED READING ON BONE PATHOLOGY

Signing out a bone pathology report is often a challenging task dotted with many pitfalls. Dr.Michael J. Klein's article " the five things you need to know about bone before signing your report"  helps pathologists avoid some of these pitfalls.
http://www.pathologyportal.org/96th/pdf/companion17h.pdf

MEDSCAPE TOP NEWS- CHUBBY GETS A BETTER RAP

Interesting review on the effects of excess weight on overall health... a point to note chubby is not bad and may even be good......

http://www.medscape.com/viewarticle/776936?src=wnl_edit_medn_wir

LATEST PLAGIARISM NEWS FROM THE ITHENTICATE BLOG

In this latest report posted by Jonathan Bailey the issue of Plagiarism as a crime has been examined ... it is a must read for all those who publish their work or  even present it ....

http://www.ithenticate.com/plagiarism-detection-blog/bid/89798/Should-Plagiarism-Ever-Be-a-Crime

ED'S HINTS FOR GOOD LECTURES

A good source for all teachers, short & interesting tips on presenting  good lectures.
Just remember to read power point slides instead of projector slides ....
There are many other worthwhile topics to read at the site, that will interest even non pathologists.

http://www.pathguy.com/goodlect.htm

A FRIEND OF IAOMP RECEIVES A GOLD MEDAL

Dr. Asitava Mondal a well wisher and friend of the Indian Association of Oral & Maxillofacial Pathologists  (IAOMP)has been elected as the Vice president of Indian Association of Pathology & Microbiology and has also been awarded a Gold medal  at Ujjain in September,2012....

CONGRATULATIONS SIR,